htrC [2018-07-16 12:41:25]

similar to quality control membrane serine protease HtrA

Locus: BSU40360

Isoelectric point: 5.32

Molecular weight: 42.63 kDa

Protein length: 400 aa

Gene length: 1200 bp

Function: unknown

Product: putative quality control membrane protease

Essential: no

Synonyms: yycK,yyxA

Genomic Context

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Categories containing this gene/protein

• Information processing → Protein synthesis, modification and degradation → Proteolysis → Protein quality control
• Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other
• Groups of genes → Membrane proteins

Gene

Coordinates: 4,147,567 → 4,148,769

The protein

Protein family

• peptidase S1B family (according to Swiss-Prot)

Paralogous protein(s)

• HtrA

Structure

• 3QO6 (from Arabidopsis thaliana, 37% identity) PubMed

Localization

• inner spore membrane PubMed

Expression and Regulation

Operons

• Genes: htrC
  Description: PubMed

  Sigma factors

  • SigG: sigma factor, PubMed, in SigG regulon

  Regulation

  • htrC transcript expressed during sporulation PubMed

• Genes: walR-walK-walH-walI-walJ-htrC
  Description: PubMed

  Regulation

  • htrC transcript expressed during sporulation PubMed

Biological materials

Mutant

• MGNA-B823 (yycK::erm), available at the NBRP B. subtilis, Japan
• BKE40360 (ΔhtrC::erm trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTCCATCCTTTCCAAG, downstream forward: _UP4_TAATAAAAGCAGTCTGGCAT
• BKK40360 (ΔhtrC::kan trpC2) available at BGSC, PubMed, upstream reverse: _UP1_CATATTCCATCCTTTCCAAG, downstream forward: _UP4_TAATAAAAGCAGTCTGGCAT

References

Reviews

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Original publications

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